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Does the pick-up and drop-off location have to be the same?

No. Rental cars booked through Hotwire may be picked up and dropped off at different locations, allowing you to enjoy a one-way trip. we now offer rental cars at both airport and non-airport locations, finding a convenient pick-up and drop-off location is easy. Once you book your rental car your drop-off location cannot be changed. At this time, Hotwire does not offer international one-way car rentals.